SUMMARY OF ANDROGENETIC ALOPECIA

Androgenetic alopecia is a common form of hair loss that affects both men and women. It is commonly referred to as male-pattern baldness when it occurs in men and female-pattern hair loss in women. The condition is characterized by a progressive thinning of the hair, leading to hair loss in specific patterns. In men, it typically begins with a receding hairline and thinning at the crown, eventually leading to baldness in some cases. In women, androgenetic alopecia causes diffuse thinning over the crown of the head, often without leading to complete baldness.

The root cause of androgenetic alopecia involves a combination of genetic, hormonal, and environmental factors. Several hormonal changes occur with aging:

• Decrease in testosterone
• Decrease in serum DHT and 5-alpha reductase
• Decrease 3AAG, a peripheral marker of DHT metabolism
• Increase in SHBG
• Decrease in androgen receptors, 5-alpha reductase type I and II activity, and aromatase in the scalp.

The hair follicles of individuals with this condition become sensitive to dihydrotestosterone (DHT), a derivative of the male hormone testosterone. DHT binds to receptors in the hair follicles, leading to a shortening of the hair growth cycle and gradual miniaturization of the follicles. Over time, the affected follicles produce thinner and shorter hairs until they stop producing hair altogether.

Genetic predisposition plays a significant role in determining who will develop androgenetic alopecia. Studies suggest that the condition can be inherited from either parent, although the exact pattern of inheritance is not fully understood. Hormonal changes, particularly related to androgens, significantly contribute to the progression of hair loss.

Treatment options for androgenetic alopecia vary based on the severity and progression of the condition.

Androgenetic alopecia can have significant psychological impacts due to changes in physical appearance. Many individuals experience decreased self-esteem and confidence as a result of hair loss. Thus, addressing the emotional and psychological aspects is also essential in managing the condition effectively.

For those looking to mitigate hair loss or slow its progression, early intervention and consultation with healthcare professionals are advisable. By understanding the nature of androgenetic alopecia and exploring the available treatment options, individuals can make informed decisions to effectively manage the condition.

**Citations:**- Sinclair, R. (2015). Male pattern androgenetic alopecia. BMJ, 351, h3273.- Norwood, O. T. (1975). Male pattern baldness: classification and incidence. Southern Medical Journal, 68(11), 1359-1365.
– Olsen, E. A. (2001). Female pattern hair loss. Journal of the American Academy of Dermatology, 45(3), S70-S80.
– Ellis, J. A., Stebbing, M., & Harrap, S. B. (2001). Genetic analysis of male pattern baldness and the 5α-reductase genes. Journal of Investigative Dermatology, 116(5), 660-665.

This condition affects up to 50 percent of males and females and is characterized by progressive loss of terminal hair of the scalp, any time after puberty.

It follows a characteristic distribution in both males and females. Hair loss is most prominent in the vertex and frontotemporal regions in males. In women, the frontal hairline is typically spared with diffuse hair loss at the crown and top of the head, with loss often marked by a wider center part.

Our practice aims to provide each patient with the best results and overall experience possible. We accomplish this by focusing on the individual. Unlike many other clinics, we do not use sales representatives.

We always want what is best for the patient. Not everyone is a candidate for every treatment. During your consultation, we will review these considerations and available options.

The relationship doesn’t end when your sessions are complete; many patients have become friends of the office and periodically send photos of their results and their families. Few other practices provide the same patient focus, physician involvement, and attention to detail.

Effective treatment for hair loss begins with finding the cause. To get an accurate diagnosis, it helps to see a certified trichologist. They have in-depth knowledge about the many causes of hair loss and experience treating the diverse causes.

Whether you are just beginning your research or have been studying hair loss and hair restoration for some time, we hope that you will find our website a valuable resource. When you are ready to speak with us regarding your specific needs we are ready to serve you.

Please give us a call at (859) 800-0771 to schedule an appointment for a personal consultation.

At Rewind Trichology, your treatment will be supervised by a certified or registered Trichologist, Associate Trichologist, or Hair Loss Consultant, along with a Nurse Practitioner and a host of other professionals.